Glossary

A glossary of terms used in the module, with brief descriptions of what each term means and how it is used, as well as a list of common abbreviations.

Spiking Data

action potential / spike

An action potential is an event in which a neuron rapidly depolarizes, initiating a cascade of events that can influence the activity of connected neurons. In general, we will refer to action potentials as ‘spikes’.

unit / single unit

A general term used to refer to a putatively individual neuron that is, for example, the source for a set of recorded spikes.

multi-unit

A general term used to refer to a situation in which there are thought to be multiple neurons contributing to a set of recorded spikes.

spike times

A representation of spiking activity based on listing the times at which spikes occur.

spike train

A representation of spiking activity in which each sample is either a 0 or 1, with 1 representing a spike.

refractory period

The amount of time after an action potential happens during which the same neuron cannot initiate another action potential.

Spike Measures

firing rate

How fast an individual unit is firing, typically measured in Hz, as spikes per second.

coefficient of variation

A measure of the variability of unit firing, reflecting the dispersion of the data around the mean.

fano factor

A measure of the variability of unit firing, as a variant of the coefficient of variation.

interspike interval (ISI)

A measure of the time interval(s) between successive spikes.

waveform / spike waveform

The shape of the action potential.

raster / raster plot

A visualization of spike activity across time, representing each spike as a vertical line.

Recording

electrode

A recording device that can measure electrical activity, that is used to collect the raw data.

extracellular recording

A recording in which the electrode sits in the extracellular fluid, outside of any individual cells.

intracellular recording

A recording in which an electrode is inserted into an individual cell.

micro-electrode

An electrode that is very small, such that if it is close enough, it can record activity from single-units that are nearby.

tetrode

A recording device with four small electrodes that can record single unit activity. The multiple wires help to differentiate different units.

sampling rate

The rate at which samples are collected on a recording device.

neurodata without borders

A standardized file type for storing neuro-electrophysiological data.

Pre-Processing

spike sorting

The process of identifying spikes and grouping them into clusters that represent putative single-neuron activity.

Measurement Units

Hertz (Hz)

A unit of frequency, used to measure the number of spikes per second.

Abbreviations

AP

Action potential.

NWB

Neurodata without borders.

ISIs

Interspike intervals.

SUA

Single-unit activity.

MUA

Multi-unit activity.

LFP

Local field potential.

ANOVA

ANalysis Of VAriance.